Bioinformatics and Integrative Genomics Group
Our research group is interested in understanding how mutations occur in cancer and what effect this has on the way genes are used. Understanding the mechanism by which these mutations form in the genome is important because it can provide us with insights into why cancers develop and how it may be prevented. We are also interested in studying how mutations can generally alter the regulation of gene expression, particularly its affect on transcription factor binding at cis-regulatory elements. Our group is interested in all cancer types, and currently have a strong focus on skin cancers, blood cancers and gastrointestinal cancers.