Dr Anchit Khanna
Field: Oncology and Carcinogenesis
Contact Details
Phone: 2 93852527
Email: a.khanna@unsw.edu.au
Tabs
Publications related to this Person
Books
Khanna A, 2011, Regulation & Clinical Relevance of Cancerous Inhibitor of Protein Phosphatase 2a (Cip2a) in Human Cancers, Tampere University Press
Journal articles
Khanna A; Thoms JAI; Stringer BW; Chung SA; Ensbey KS; Jue TR; Jahan Z; Subramanian S; Anande G; Shen H; Unnikrishnan A; McDonald KL; Day BW; Pimanda JE, 2020, 'Constitutive CHK1 Expression Drives a pSTAT3-CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth', Molecular cancer research : MCR, vol. 18, pp. 709 - 722, http://dx.doi.org/10.1158/1541-7786.MCR-19-0934
Khanna A; Pimanda JE, 2016, 'Clinical significance of cancerous inhibitor of protein phosphatase 2A in human cancers', International Journal of Cancer, vol. 138, pp. 525 - 532, http://dx.doi.org/10.1002/ijc.29431
Khanna A, 2015, 'DNA damage in cancer therapeutics: A boon or a curse?', Cancer Research, vol. 75, pp. 2133 - 2138, http://dx.doi.org/10.1158/0008-5472.CAN-14-3247
Marks-Bluth J; Khanna A; Chandrakanthan V; Thoms J; Bee T; Eich C; Kang YC; Knezevic K; Qiao Q; Fitch S; Oxburgh L; Ottersbach K; Dzierzak E; de Bruijn MFTR; Pimanda JE, 2015, 'SMAD1 and SMAD5 expression is coordinately regulated by FLI1 and GATA2 during endothelial development', Molecular and Cellular Biology, vol. 35, pp. 2165 - 2172, http://dx.doi.org/10.1128/MCB.00239-15
Khanna A; Rane JK; Kivinummi KK; Urbanucci A; Helenius MA; Tolonen TT; Saramäki OR; Latonen L; Manni V; Pimanda JE; Maitland NJ; Westermarck J; Visakorpi T, 2015, 'CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations', Oncotarget, vol. 6, pp. 19661 - 19670, http://dx.doi.org/10.18632/oncotarget.3875
Khanna A; Patil R; Deshmukh A, 2014, 'Assessment of the potential of pathological stains in human prostate cancer', Journal of Clinical and Diagnostic Research, vol. 8, pp. 124 - 128, http://dx.doi.org/10.7860/JCDR/2014/7002.3938
Khanna A; Pimanda JE; Westermarck J, 2013, 'Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target', Cancer Research, vol. 73, pp. 6548 - 6553, http://dx.doi.org/10.1158/0008-5472.CAN-13-1994
Khanna A; Kauko O, Bockelman C, Laine A, Schreck I, Partanen JI, Szwajda A, Bormann S, Bilgen T, Helenius M, Pokharel YR, Pimanda J, Russel MR, Haglund C, Cole KA, Klefstrom J, Aittokallio T, Weiss C, Ristimaki A, Visakorpi T, Westermarck J. , 2013, 'Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells.', Cancer Research, vol. 73, pp. 6757 - 6769, http://dx.doi.org/10.1158/0008-5472.CAN-13-1002
Laine A; Sihto H; Come C; Rosenfeldt M; Zwalinska A; Niemela M; Khanna A; Chan E; Kahari V; Kellokumpu-lehtinen P; J sansom O; i evan G; R junttila M; M ryan K; marine J; Joensuu H; Westermarck J, 2013, 'Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1', CANCER DISCOVERY, vol. 3, pp. 182 - 197, http://cancerdiscovery.aacrjournals.org/content/3/2/182.abstract
Mathiasen D; Egebjerg C; Andersen SH; Rafn B; Puustinen B; Khanna A, 2012, 'Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation.', Oncogene, vol. 31, pp. 390 - 401, http://dx.doi.org/10.1038/onc.2011.230
Khanna A, 2011, 'ETS1 mediates MEK1/2-dependent overexpression of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human cancer cells.', PLoS ONE, vol. 6, pp. e17979, http://dx.doi.org/10.1371/journal.pone.0017979
Khanna A, 2010, 'KIAA1524', Atlas of Genetics and Cytogenetics in Oncology and Haematology, vol. 14, http://documents.irevues.inist.fr/bitstream/handle/2042/44873/01-2010-KIAA1524ID44402ch3q13.pdf?sequence=5
Khanna A; Böckelman C; Hemmes A; Junttila MR; Wiksten JP; Lundin M; Junnila S; Murphy DJ; Evan GI; Haglund C; Westermarck J; Ristimäki A, 2009, 'MYC-dependent regulation and prognostic role of CIP2A in gastric cancer', Journal of the National Cancer Institute, vol. 101, pp. 793 - 805, http://dx.doi.org/10.1093/jnci/djp103
Conference Papers
Khanna A; Stringer B; Ensbey K; Jahaan Z; Boyd A; McDonald K; Day B; Pimanda J, 2015, 'Clinical relevance of DNA damage modulator checkpoint kinase 1 (CHK1) and cancerous inhibitor of protein phosphatase 2A (CIP2A) in human gliomas', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, Singapore, SINGAPORE, pp. 34 - 34, presented at Asia Congress of the European-Society-for-Medical-Oncology (ESMO), Singapore, SINGAPORE, 18 December 2015 - 21 December 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000367158700117&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Khanna A; Stringer B; Day B; Ensbey K; Shen H; Boyd A; McDonald K; Pimanda J, 2014, ''Keeping glioblastoma (GBM) in check by targeting the CHK1-STAT3-CIP2A axis',', in presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, CA, 5 - 9 April 2014, 05th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, presented at 05th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-1600
Dun MD; Smith AM; Kahl RGS; Smith ND; Khanna A; Don AS; Toop HF; Morris JC; Verrills NM, 2013, 'Unraveling the mechanism of action: drugs that activate the tumor suppressor 2A.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-2038
Khanna A; Camilla Böckelman, Ilona Schreck, Carsten Weiss, Tapio Visakorpi, Ari Ristimäki, and Jukka Westermarck , 2011, 'Abstract 4194: Constitutive DNA-damage signaling promotes cancer cell proliferation through Chk1-CIP2A pathway independent of ATM-ATR', in AACR 102nd Annual Meeting 2011-- Apr 2-6, 2011; Orlando, FL, Cancer Research, 02 April 2011 - 06 April 2011, http://cancerres.aacrjournals.org/cgi/content/meeting_abstract/71/8_MeetingAbstracts/4194
Khanna A, 2010, '859 Constitutive DNA-damage signaling promotes cancer cell proliferation through Chk1-CIP2A pathway', in 21st Meeting of the European Association for Cancer Research, 26 June 2010 - 29 June 2010
Khanna A, 2009, '6650 Myc-dependent regulation and prgonostic role of Myc stabilizing protein, CIP2A, in human gastric cancer', in Joint ECCO 15 – 34th ESMO Multidisciplinary Congress, 20 September 2009 - 24 September 2009, http://www.sciencedirect.com/science/article/pii/S1359634909713710
Khanna A, 2008, 'CIP2A (Cancerous Inhibitor of Protein Phosphatase 2A) promotes gastric carcinogenesis', in CIP2A (Cancerous Inhibitor of Protein Phosphatase 2A) promotes gastric carcinogenesis, European Journal of Cancer Supplements, Lyon, presented at EACR 20, Lyon, 05 July 2008 - 08 July 2008
Conference Posters
Khanna A, 2011, 'Abstract 4194: Constitutive DNA-damage signaling promotes cancer cell proliferation through Chk1-CIP2A pathway independent of ATM-ATR', in Abstract 4194: Constitutive DNA-damage signaling promotes cancer cell proliferation through Chk1-CIP2A pathway independent of ATM-ATR, AACR Annual Meeting, Orlando, Florida , USA, presented at AACR Annual Meeting, Orlando, Florida , USA, 02 April 2011 - 06 April 2011, http://cancerres.aacrjournals.org/cgi/content/meeting_abstract/71/8_MeetingAbstracts/4194
Conference Presentations
Khanna A; Stringer B; Day B; Ensbey K; Boyd A; McDonald K; Pimanda J, 2014, 'Targeting the CHK1-CIP2A axis to treat Glioblastoma (GBM)', in Targeting the CHK1-CIP2A axis to treat Glioblastoma (GBM), Lorne Cancer conference 2014, presented at Lorne Cancer conference 2014, 13 February 2014 - 14 February 2014
Khanna A, 2011, 'Oral Presentation - DNA damage response kinase CHK1 drives widespread inhibition of tumour suppressor PP2A via CIP2A', in Oral Presentation - DNA damage response kinase CHK1 drives widespread inhibition of tumour suppressor PP2A via CIP2A, Receptor Program Annual Symposium, Turku , Finland, presented at Receptor Program Annual Symposium, Turku , Finland, 15 September 2011 - 15 September 2011
Khanna A; Böckelman C; Hemmes A; Junttila M; Wiksten J; Lundin M; Evan G; Haglund C; Westermarck J; Ristimaki A, 2010, 'MYC-dependent regulation and prognostic role of MYC stabilizing protein, CIP2A, in human gastric cancer', in MYC-dependent regulation and prognostic role of MYC stabilizing protein, CIP2A, in human gastric cancer, Annual conference of National Cancer Research Institute, Liverpool. U.K., presented at Annual conference of National Cancer Research Institute, Liverpool. U.K., 02 November 2010 - 05 November 2010
Khanna A, 2009, 'C-Myc-Dependent Regulation and Prognostic Role of c-Myc Stabilizing Protein CIP2A, in Human Gastric Cancer', in C-Myc-Dependent Regulation and Prognostic Role of c-Myc Stabilizing Protein CIP2A, in Human Gastric Cancer, KEYSTONE SYMPOSIA: Deregulation of Transcription in Cancer: Controlling Cell Fate Decisions, Killarney, IRELAND, presented at KEYSTONE SYMPOSIA: Deregulation of Transcription in Cancer: Controlling Cell Fate Decisions, Killarney, IRELAND, 21 June 2009 - 25 June 2009
Conference Abstracts
Khanna A; Stringer B; Day B; Ensbey K; Shen H; Boyd A; McDonald KL; Pimanda J, 2014, 'Keeping GBM in check by targeting CHK1-CIP2A axis', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Chicago, IL, Vol. 32, presented at 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL, 30 May 2014 - 03 June 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000358613202702&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Reports
Khanna A, 2010, European Association for Cancer Research Yearbook -2010:The EACR Cancer Researcher Award - Highly Commended; ECCO15-34 ESMO, Berlin, http://www.eacr.org/news/2010/3-EACR%20Cancer%20Researcher%20Award.pdf
Khanna A, 2009, European Association for Cancer Research Annual Newsletter :Role of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Gastric Carcinogenesis, http://www.eacr.org/news/2009/12-EACR-20%20Poster%20Prize%20Winners.pdf
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