Dr Jason Wong

Thoms JAI; Truong P; Subramanian S; Knezevic K; Harvey G; Huang Y; Seneviratne JA; Carter DR; Joshi S; Skhinas J; Chacon D; Shah A; de Jong I; Beck D; Göttgens B; Larsson J; Wong JWH; Zanini F; Pimanda JE, 2021, 'Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells', Blood, vol. 138, pp. 1441 - 1455, http://dx.doi.org/10.1182/blood.2020009707

Krilis M; Qi M; Ioannou Y; Zhang JY; Ahmadi Z; Wong JWH; Vlachoyiannopoulos PG; Moutsopoulos HM; Koike T; Sturgess AD; Chong BH; Krilis SA; Giannakopoulos B, 2021, 'Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk', Journal of Autoimmunity, vol. 122, pp. 102675, http://dx.doi.org/10.1016/j.jaut.2021.102675

Gifford G; Hesson L; Wong JWH; Carroll A; Gabrielli S; Bai LJ; Xia W; Stevenson W; Greenwood M, 2021, 'Poor mobilization of autologous CD34⁺ peripheral blood stem cells in haematology patients undergoing autologous stem cell transplantation is associated with the presence of variants in genes implicated in clonal haematopoiesis of indeterminant potential', British Journal of Haematology, vol. 193, pp. 841 - 844, http://dx.doi.org/10.1111/bjh.17316

Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Srivastava P; Potas JR; Hung T; Power C; Hardy P; Ma DD; Kilian KA; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE, 2021, 'Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine', Science Advances, vol. 7, pp. eabd1929 - eabd1929, http://dx.doi.org/10.1126/sciadv.abd1929

Tsang O; Wong JWH, 2021, 'Proteogenomic interrogation of cancer cell lines: an overview of the field', Expert Review of Proteomics, vol. 18, pp. 221 - 232, http://dx.doi.org/10.1080/14789450.2021.1914594

Thoms J; Truong P; Subramanian S; Knezevic K; Harvey G; Huang Y; Seneviratne J; Carter D; Joshi S; Skhinas J; Chacon D; Shah A; de Jong I; Beck D; Göttgens B; Larsson J; Wong J; Zanini F; Pimanda J, 2021, '3034 – DISRUPTION OF A GATA2, TAL1, ERG REGULATORY CIRCUIT PROMOTES ERYTHROID TRANSITION IN HEALTHY AND LEUKEMIC STEM CELLS', Experimental Hematology, vol. 100, pp. S59 - S59, http://dx.doi.org/10.1016/j.exphem.2021.12.255

Yan HHN; Siu HC; Ho SL; Yue SSK; Gao Y; Tsui WY; Chan D; Chan AS; Wong JWH; Man AHY; Lee BCH; Chan ASY; Chan AKW; Hui HS; Cheung AKL; Law WL; Lo OSH; Yuen ST; Clevers H; Leung SY, 2020, 'Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles', Gut, vol. 69, pp. 2165 - 2179, http://dx.doi.org/10.1136/gutjnl-2019-320019

Zhu X; Fang H; Gladysz K; Barbour J; Wong J, 2020, 'Overexpression of transposable elements is associated with immune overdrive and poor clinical outcome in colorectal cancer patients', , http://dx.doi.org/10.1101/2020.07.14.20129031

Anande G; Deshpande NP; Mareschal S; Batcha AMN; Hampton HR; Herold T; Lehmann S; Wilkins MR; Wong JWH; Unnikrishnan A; Pimanda JE, 2020, 'RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia', Clinical Cancer Research, vol. 26, pp. 3597 - 3607, http://dx.doi.org/10.1158/1078-0432.CCR-20-0184

Yeola A; Subramanian S; Oliver R; Lucas C; Thoms J; Yan F; Olivier J; Chacon D; Tursky M; Hung T; Power C; Hardy P; Ma D; McCarroll J; Kavallaris M; Hesson L; Beck D; Curtis D; Wong JWH; Hardeman E; Walsh W; Mobbs R; Chandrakanthan V; Pimanda J, 2020, 'Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine', , http://dx.doi.org/10.1101/2020.06.04.130872

Fang H; Barbour JA; Poulos RC; Katainen R; Aaltonen LA; Wong JWH, 2020, 'Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer', PLoS genetics, vol. 16, pp. e1008572, http://dx.doi.org/10.1371/journal.pgen.1008572

Anande G; Deshpande N; Mareschal S; Batcha A; Hampton H; Herold T; Lehmann S; Wilkins M; Wong JWH; Unnikrishnan A; Pimanda J, 2020, 'RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML', , http://dx.doi.org/10.1101/2020.01.10.895714

Wong M; Sun Y; Xi Z; Milazzo G; Poulos RC; Bartenhagen C; Bell JL; Mayoh C; Ho N; Tee AE; Chen X; Li Y; Ciaccio R; Liu PY; Jiang CC; Lan Q; Jayatilleke N; Cheung BB; Haber M; Norris MD; Zhang XD; Marshall GM; Wang JY; Hüttelmaier S; Fischer M; Wong JWH; Xu H; Perini G; Dong Q; George RE; Liu T, 2019, 'JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma', Nature Communications, vol. 10, pp. 3319, http://dx.doi.org/10.1038/s41467-019-11132-w

Bao X; Liu Z; Zhang W; Gladysz K; Fung YME; Tian G; Xiong Y; Wong JWH; Yuen KWY; Li XD, 2019, 'Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics', Molecular Cell, vol. 76, pp. 660 - 675.e9, http://dx.doi.org/10.1016/j.molcel.2019.08.018

Guo D; Lui GYL; Lai SL; Wilmott JS; Tikoo S; Jackett LA; Quek C; Brown DL; Sharp DM; Kwan RYQ; Chacon D; Wong JH; Beck D; van Geldermalsen M; Holst J; Thompson JF; Mann GJ; Scolyer RA; Stow JL; Weninger W; Haass NK; Beaumont KA, 2019, 'RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes', International Journal of Cancer, vol. 144, pp. 3070 - 3085, http://dx.doi.org/10.1002/ijc.32064

Poulos RC; Perera D; Packham D; Shah A; Janitz C; Pimanda JE; Hawkins N; Ward RL; Hesson LB; Wong JWH, 2019, 'Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing', JNCI CANCER SPECTRUM, vol. 3, http://dx.doi.org/10.1093/jncics/pkz012

Poulos RC; Wong JWH, 2019, 'Finding cancer driver mutations in the era of big data research', Biophysical Reviews, vol. 11, pp. 21 - 29, http://dx.doi.org/10.1007/s12551-018-0415-6

Wong JWH, 2019, 'Assessing the evolutionary conservation of protein disulphide bonds', Methods Mol Biol, vol. 1967, pp. 9 - 19, http://dx.doi.org/10.1007/978-1-4939-9187-7_2

Morris MJ; Hesson LB; Poulos RC; Ward RL; Wong JWH; Youngson NA, 2018, 'Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation', Biomarker Research, vol. 6, pp. 37, http://dx.doi.org/10.1186/s40364-018-0151-x

Jing D; Huang Y; Liu X; Sia KCS; Zhang JC; Tai X; Wang M; Toscan CE; McCalmont H; Evans K; Mayoh C; Poulos RC; Span M; Mi J; Zhang C; Wong JWH; Beck D; Pimanda JE; Lock RB, 2018, 'Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia', Cancer Cell, vol. 34, pp. 906 - 921.e8, http://dx.doi.org/10.1016/j.ccell.2018.11.002

Yan HHN; Siu HC; Law S; Ho SL; Yue SSK; Tsui WY; Chan D; Chan AS; Ma S; Lam KO; Bartfeld S; Man AHY; Lee BCH; Chan ASY; Wong JWH; Cheng PSW; Chan AKW; Zhang J; Shi J; Fan X; Kwong DLW; Mak TW; Yuen ST; Clevers H; Leung SY, 2018, 'A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening', Cell Stem Cell, vol. 23, pp. 882 - 897.e11, http://dx.doi.org/10.1016/j.stem.2018.09.016

Krilis M; Qi M; Qi J; Wong JWH; Guymer R; Liew G; Hunyor AP; Madigan M; McCluskey P; Weaver J; Krilis SA; Giannakopoulos B, 2018, 'Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration', Free Radical Biology and Medicine, vol. 129, pp. 237 - 246, http://dx.doi.org/10.1016/j.freeradbiomed.2018.09.034

Poulos RC; Wong YT; Ryan R; Pang H; Wong JWH, 2018, 'Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations', PLoS Genetics, vol. 14, pp. e1007779, http://dx.doi.org/10.1371/journal.pgen.1007779

Liu Q; Thoms JAI; Nunez AC; Huang Y; Knezevic K; Packham D; Poulos RC; Williams R; Beck D; Hawkins NJ; Ward RL; Wong JWH; Hesson LB; Sloane MA; Pimanda JE, 2018, 'Disruption of a 35 KB enhancer impairs CTCF binding and MLH1 expression in colorectal cells', Clinical Cancer Research, vol. 24, pp. 4602 - 4611, http://dx.doi.org/10.1158/1078-0432.CCR-17-3678

Beck D; Thoms JAI; Palu C; Herold T; Shah A; Olivier J; Boelen L; Huang Y; Chacon D; Brown A; Babic M; Hahn C; Perugini M; Zhou X; Huntly BJ; Schwarzer A; Klusmann JH; Berdel WE; Wörmann B; Büchner T; Hiddemann W; Bohlander SK; To LB; Scott HS; Lewis ID; D'Andrea RJ; Wong JWH; Pimanda JE, 2018, 'A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients', Leukemia, vol. 32, pp. 263 - 272, http://dx.doi.org/10.1038/leu.2017.210

Pijning AE; Chiu J; Yeo RX; Wong JWH; Hogg PJ, 2018, 'Identification of allosteric disulfides from labile bonds in X-ray structures', Royal Society Open Science, vol. 5, http://dx.doi.org/10.1098/rsos.171058

Zeraati M; Moye AL; Wong JWH; Perera D; Cowley MJ; Christ DU; Bryan TM; Dinger ME, 2017, 'Cancer-Associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-00739-y

Schwarzer A; Emmrich S; Schmidt F; Beck D; Ng M; Reimer C; Adams FF; Grasedieck S; Witte D; Käbler S; Wong JWH; Shah A; Huang Y; Jammal R; Maroz A; Jongen-Lavrencic M; Schambach A; Kuchenbauer F; Pimanda JE; Reinhardt D; Heckl D; Klusmann JH, 2017, 'The non-coding RNA landscape of human hematopoiesis and leukemia', Nature Communications, vol. 8, http://dx.doi.org/10.1038/s41467-017-00212-4

Unnikrishnan A; Papaemmanuil E; Beck D; Deshpande NP; Verma A; Kumari A; Woll PS; Richards LA; Knezevic K; Chandrakanthan V; Thoms JAI; Tursky ML; Huang Y; Ali Z; Olivier J; Galbraith S; Kulasekararaj AG; Tobiasson M; Karimi M; Pellagatti A; Wilson SR; Lindeman R; Young B; Ramakrishna R; Arthur C; Stark R; Crispin P; Curnow J; Warburton P; Roncolato F; Boultwood J; Lynch K; Jacobsen SEW; Mufti GJ; Hellstrom-Lindberg E; Wilkins MR; MacKenzie KL; Wong JWH; Campbell PJ; Pimanda JE, 2017, 'Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes', Cell Reports, vol. 20, pp. 572 - 585, http://dx.doi.org/10.1016/j.celrep.2017.06.067

Poulos RC; Olivier J; Wong JWH, 2017, 'The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes', Nucleic Acids Research, vol. 45, pp. 7786 - 7795, http://dx.doi.org/10.1093/nar/gkx463

Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D; Liu PY; Zhang XD; Hüttelmaier S; Wong JWH; Wang J; Polly P; Perini G; Scarlett CJ; Liu T, 2017, 'The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription', Cancer Research, vol. 77, pp. 2522 - 2533, http://dx.doi.org/10.1158/0008-5472.CAN-16-1663

Poulos R; Olivier J; Wong J, 2017, 'CpG methylation accounts for genome-wide C>T mutation variation and cancer driver formation across cancer types', CpG methylation accounts for genome-wide C>T mutation variation and cancer driver formation across cancer types, http://dx.doi.org/10.1101/106872

Krilis M; Qi M; Madigan MC; Wong JWH; Abdelatti M; Guymer RH; Whitelock J; McCluskey P; Zhang P; Qi J; Hunyor AP; Krilis SA; Giannakopoulos B, 2017, 'Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration', Oncotarget, vol. 8, pp. 49016 - 49032, http://dx.doi.org/10.18632/oncotarget.14940

Ma S; Menon R; Poulos RC; Wong JWH, 2017, 'Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples', Oncotarget, vol. 8, pp. 95841 - 95852, http://dx.doi.org/10.18632/oncotarget.21339

Chandrakanthan V; Qiao Q; Chan Kang Y; Knezevic K; Oliver R; Loo C; Anande G; Lee B; Walsh W; Power C; Wong J; Pimanda J, 2017, 'Declined presentation characterisation of stromal cell populations in the foetal liver and their contributions to embryonic haematopoietic and vascular development', Experimental Hematology, vol. 53, pp. S118 - S118, http://dx.doi.org/10.1016/j.exphem.2017.06.295

Hesson LB; Ng B; Zarzour P; Srivastava S; Kwok CT; Packham D; Nunez AC; Beck D; Ryan R; Dower A; Ford CE; Pimanda JE; Sloane MA; Hawkins NJ; Bourke MJ; Wong JWH; Ward RL, 2016, 'Integrated genetic, epigenetic, and transcriptional profiling identifies molecular pathways in the development of laterally spreading tumors', Molecular Cancer Research, vol. 14, pp. 1217 - 1228, http://dx.doi.org/10.1158/1541-7786.MCR-16-0175

Unnikrishnan A; Guan YF; Huang Y; Beck D; Thoms JAI; Peirs S; Knezevic K; Ma S; De Walle IV; De Jong IDE; Ali Z; Zhong L; Raftery MJ; Taghon T; Larsson J; MacKenzie KL; Van Vlierberghe P; Wong JWH; Pimanda JE, 2016, 'A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network', Nucleic Acids Research, vol. 44, pp. 10644 - 10661, http://dx.doi.org/10.1093/nar/gkw804

Nasrallah R; Fast EM; Solaimani P; Knezevic K; Eliades A; Patel R; Thambyrajah R; Unnikrishnan A; Thoms J; Beck D; Vink CS; Smith A; Wong J; Shepherd M; Kent D; Roychoudhuri R; Paul F; Klippert J; Hammes A; Willnow T; Göttgens B; Dzierzak E; Zon LI; Lacaud G; Kouskoff V; Pimanda JE, 2016, 'Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes', Blood, vol. 128, pp. 1928 - 1939, http://dx.doi.org/10.1182/blood-2016-02-697870

Huang Y; Thoms JAI; Tursky ML; Knezevic K; Beck D; Chandrakanthan V; Suryani S; Olivier J; Boulton A; Glaros EN; Thomas SR; Lock RB; MacKenzie KL; Bushweller JH; Wong JWH; Pimanda JE, 2016, 'MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation', Leukemia, vol. 30, pp. 1552 - 1561, http://dx.doi.org/10.1038/leu.2016.55

Srivastava S; Ludwig AK; Wong JWH; Hesson LB, 2016, 'An investigation of the potential for epigenetic inactivation by transcription read-through in a sporadic colorectal cancer', Gene, vol. 585, pp. 154 - 158, http://dx.doi.org/10.1016/j.gene.2016.03.031

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Perera D; Poulos RC; Shah A; Beck D; Pimanda JE; Wong JWH, 2016, 'Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes', Nature, vol. 532, pp. 259 - 263, http://dx.doi.org/10.1038/nature17437

Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P; Tunningley R; Whittle B; Yeung AWS; Chandrakanthan V; Hesson L; Chen V; Wong JWH; Purton LE; Ward RL; Thomas SR; Pimanda JE, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15

Poulos RC; Wong JWH, 2016, 'Mutation hotspots in cis-regulatory regions in cancer', Oncoscience, vol. 3, pp. 318 - 319, http://dx.doi.org/10.18632/oncoscience.325

Sun Y; Bell JL; Carter D; Gherardi S; Poulos RC; Milazzo G; Wong JWH; Al-Awar R; Tee AE; Liu PY; Liu B; Atmadibrata B; Wong M; Trahair T; Zhao Q; Shohet JM; Haupt Y; Schulte JH; Brown PJ; Arrowsmith CH; Vedadi M; MacKenzie KL; Hüttelmaier S; Perini G; Marshall GM; Braithwaite A; Liu T, 2015, 'WDR5 supports an N-myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma', Cancer Research, vol. 75, pp. 5143 - 5154, http://dx.doi.org/10.1158/0008-5472.CAN-15-0423

Ma S; Downard KM; Wong JWH, 2015, 'FluClass: A novel algorithm and approach to score and visualize the phylogeny of the influenza virus using mass spectrometry', Analytica Chimica Acta, vol. 895, pp. 54 - 61, http://dx.doi.org/10.1016/j.aca.2015.09.004

Poulos RC; Thoms JAI; Shah A; Beck D; Pimanda JE; Wong JWH, 2015, 'Systematic screening of promoter regions pinpoints functional cis-regulatory mutations in a cutaneous melanoma genome', Molecular Cancer Research, vol. 13, pp. 1218 - 1226, http://dx.doi.org/10.1158/1541-7786.MCR-15-0146

Zarzour P; Boelen L; Luciani F; Beck D; Sakthianandeswaren A; Mouradov D; Sieber OM; Hawkins NJ; Hesson LB; Ward RL; Wong JWH, 2015, 'Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas', Genes Chromosomes and Cancer, vol. 54, pp. 303 - 314, http://dx.doi.org/10.1002/gcc.22243

Tursky ML; Beck D; Thoms JAI; Huang Y; Kumari A; Unnikrishnan A; Knezevic K; Evans K; Richards LA; Lee E; Morris J; Goldberg L; Izraeli S; Wong JWH; Olivier J; Lock RB; MacKenzie KL; Pimanda JE, 2015, 'Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias', Leukemia, vol. 29, pp. 819 - 827, http://dx.doi.org/10.1038/leu.2014.299

Hesson LB; Packham D; Kwok CT; Nunez AC; Ng B; Schmidt C; Fields M; Wong JW; Sloane MA; Ward RL, 2015, 'Lynch Syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.', Human Mutation, vol. 36, pp. 622 - 630, http://dx.doi.org/10.1002/humu.22785

Ng JY; Wong JWH, 2015, 'Bioorthogonal labelling of 3-nitrotyrosine in peptides and proteins through diazotisation mediated azidation', Organic and Biomolecular Chemistry, vol. 13, pp. 374 - 378, http://dx.doi.org/10.1039/c4ob02133a

Poulos RC; Sloane MA; Hesson LB; Wong JWH, 2015, 'The search for cis-regulatory driver mutations in cancer genomes', Oncotarget, vol. 6, pp. 32509 - 32525, http://dx.doi.org/10.18632/oncotarget.5085

Jing RBAB, 2015, 'Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells', Blood, vol. 125, pp. 273 - 283, http://dx.doi.org/10.1182/blood-2014-05-576470

Hesson LB; Sloane MA; Wong JWH; Nunez AC; Srivastava S; Ng B; Hawkins NJ; Bourke MJ; Ward RL, 2014, 'Altered promoter nucleosome positioning is an early event in gene silencing', Epigenetics, vol. 9, pp. 1422 - 1430, http://dx.doi.org/10.4161/15592294.2014.970077

Sloane MA; Wong JWH; Perera D; Nunez AC; Pimanda JE; Hawkins NJ; Sieber OM; Bourke MJ; Hesson LB; Ward RL, 2014, 'Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia', Epigenetics, vol. 9, pp. 1092 - 1100, http://dx.doi.org/10.4161/epi.29222

Butera D; Cook K; Chiu J; Wong JWH; Hogg PJ, 2014, 'Control of blood proteins by functional disulfide bonds', Blood, vol. 123, pp. 2000 - 2007, http://dx.doi.org/10.1182/blood-2014-01-549816

Chiu J; Wong JWH; Gerometta M; Hogg PJ, 2014, 'Mechanism of dimerization of a recombinant mature vascular endothelial growth factor C', Biochemistry, vol. 53, pp. 7 - 9, http://dx.doi.org/10.1021/bi401518b

Chacon D; Beck D; Perera D; Wong JWH; Pimanda JE, 2014, 'BloodChIP: A database of comparative genome-wide transcription factor binding profiles in human blood cells', Nucleic Acids Research, vol. 42, http://dx.doi.org/10.1093/nar/gkt1036

Chiu J; Wong JWH; Hogg PJ, 2014, 'Redox regulation of Methionine aminopeptidase 2 activity', Journal of Biological Chemistry, vol. 289, pp. 15035 - 15043, http://dx.doi.org/10.1074/jbc.M114.554253

Perera D; Chacon D; Thoms JA; Poulos RC; Shlien A; Beck D; Campbell PJ; Pimanda JE; Wong JW, 2014, 'Oncocis: Annotation of cis-regulatory mutations in cancer', Genome Biology, vol. 15, http://dx.doi.org/10.1186/s13059-014-0485-0

Ng JY; Chiu J; Hogg PJ; Wong JWH, 2013, 'Tyrosine nitration moderates the peptidase activity of human methionyl aminopeptidase 2', Biochemical and Biophysical Research Communications, vol. 440, pp. 37 - 42, http://dx.doi.org/10.1016/j.bbrc.2013.09.035

Wong JJL; Ritchie W; Ebner OA; Selbach M; Wong JWH; Huang Y; Gao D; Pinello N; Gonzalez M; Baidya K; Thoeng A; Khoo TL; Bailey CG; Holst J; Rasko JEJ, 2013, 'XOrchestrated intron retention regulates normal granulocyte differentiation', Cell, vol. 154, pp. 583 - 595, http://dx.doi.org/10.1016/j.cell.2013.06.052

Beck D; Thoms JAI; Perera D; Schütte J; Unnikrishnan A; Knezevic K; Kinston SJ; Wilson NK; O'Brien TA; Göttgens B; Wong JWH; Pimanda JE, 2013, 'Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes', Blood, vol. 122, pp. e12 - e22, http://dx.doi.org/10.1182/blood-2013-03-490425

Lun A; Swaminathan K; Wong JWH; Downard KM, 2013, 'Mass trees: A new phylogenetic approach and algorithm to chart evolutionary history with mass spectrometry', Analytical Chemistry, vol. 85, pp. 5475 - 5482, http://dx.doi.org/10.1021/ac4005875

Diffner E; Beck D; Gudgin E; Thoms JA; Knezevic K; Pridans C; Foster S; Goode D; Lim WK; boelen L; Metzeler KH; Micklem G; Bohlander SK; Buske C; Burnett A; Ottersbach K; Vassiliou GS; Olivier J; Wong JWH; Goettgens B; Huntly BJ; Pimanda JE, 2013, 'Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia', Blood, vol. 121, pp. 2289 - 2300, http://dx.doi.org/10.1182/blood-2012-07-446120

Ng J; Boelen L; Wong JWH, 2013, 'Bioinformatics analysis reveals biophysical and evolutionary insights into the 3-nitrotyrosine post-translational modification in the human proteome', Open Biology, vol. 3, http://dx.doi.org/10.1098/rsob.120148

Giannakopoulos B; Gao L; Qi M; Wong JW; Yu D; Vlachoyiannopoulos P; Moutsopoulos HM; Atsumi T; Koike T; Hogg PJ; Qi JC; Krilis S, 2012, 'Factor XI is a substrate for oxidoreductases: Enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.', Journal of Autoimmunity, vol. 39, pp. 121 - 129, http://dx.doi.org/10.1016/j.jaut.2012.05.005

Beck D; Brandl MB; boelen L; Unnikrishnan A; Pimanda JE; Wong JWH, 2012, 'Signal analysis for genome-wide maps of histone modifications measured by ChIP-seq', Bioinformatics, vol. 28, pp. 1062 - 1069, http://dx.doi.org/10.1093/bioinformatics/bts085

Wong JWH; Abuhusain H; McDonald K; Don AS, 2012, 'MMSAT: Automated Quantification of Metabolites in Selected Reaction Monitoring Experiments', Analytical Chemistry, vol. 84, pp. 470 - 474, http://dx.doi.org/10.1021/ac2026578

Lun A; Wong JWH; Downard KM, 2012, 'FluShuffle and FluResort: new algorithms to identify reassorted strains of the influenza virus by mass spectrometry', BMC bioinformatics, vol. 13, http://dx.doi.org/10.1186/1471-2105-13-208

Ganderton T; Wong JWH; Schroeder C; Hogg PJ, 2011, 'Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain', Blood, vol. 118, pp. 5312 - 5318, http://dx.doi.org/10.1182/blood-2011-06-360297

Hejazi L; Wong JWH; Cheng D; Proschogo NW; Ebrahimi Mohammadi D; Garner B; Don AS, 2011, 'Mass and Relative Elution Time Profiling: Two Dimensional Analysis of Sphingolipids in Alzheimer's Disease Brains', Biochemical Journal, vol. 438, pp. 165 - 175, http://dx.doi.org/10.1042/BJ20110566

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong JWH; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S, 2011, 'Redox control of â2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1.', Journal of Thrombosis and Haemostasis, vol. 8, pp. 1754 - 1762, http://dx.doi.org/10.1111/j.1538-7836.2010.03944.x

Thoms JAI; Birger Y; Foster S; Knezevic K; Kirshenbaum Y; Chandrakanthan V; Jonquieres G; Spensberger D; Wong JW; Oram SH; Kinston SJ; Groner Y; Lock RB; MacKenzie KL; Gottgens B; Izraeli S; Pimanda JE, 2011, 'ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer', Blood, vol. 117, pp. 7079 - 7089, http://dx.doi.org/10.1182/blood-2010-12-317990

Park D; Don AS; Massamiri T; Karwa AK; Warner B; Macdonald J; Hemenway C; Naik A; Kuan K; Dilda P; Wong JW; Camphausen K; Chinen L; Dyszlewski M; Hogg PJ, 2011, 'Noninvasive Imaging of Cell Death Using an Hsp90 Ligand', Journal of the American Chemical Society, vol. 133, pp. 2832 - 2835, http://dx.doi.org/10.1021/ja110226y

Wong JWH; Ho SYW; Hogg PJ, 2011, 'Disulfide bond acquisition through eukaryotic protein evolution', Molecular Biology and Evolution, vol. 28, pp. 327 - 334, http://dx.doi.org/10.1093/molbev/msq194

Azimi I; Wong JWH; Hogg PJ, 2011, 'Control of mature protein function by allosteric disulfide bonds', Antioxidants and Redox Signaling, vol. 14, pp. 113 - 126, http://dx.doi.org/10.1089/ars.2010.3620

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong J; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S, 2010, 'Beta 2 glycoprotein I is a substrate of thiol oxidoreductases', Blood, vol. 116, pp. 1995 - 1997, http://dx.doi.org/10.1182/blood-2010-02-271494

Azimi I; Matthias LJ; Center R; Wong JWH; Hogg PJ, 2010, 'Disulfide bond that constrains the HIV-1 gp120 V3 domain is cleaved by thioredoxin', The Journal of Biological Chemistry, vol. 285, pp. 40072 - 40080, http://dx.doi.org/10.1074/jbc.M110.185371

Schwahn AB; Wong JWH; Downard KM, 2010, 'Rapid typing and subtyping of vaccine strains of the influenza virus with high resolution mass spectrometry', European Journal of Mass Spectrometry, vol. 16, pp. 321 - 329, http://dx.doi.org/10.1255/ejms.1056

Porro A; Haber M; Diolaiti D; Iraci N; Henderson M; Gherardi S; Valli E; Munoz M; Xue C; Flemming C; Schwab M; Wong JH; Marshall GM; Della valle G; Norris MD; Perini G, 2010, 'Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells', The Journal of Biological Chemistry, vol. 285, pp. 19532 - 19543, http://dx.doi.org/10.1074/jbc.M109.078584

Schwahn AB; Wong JWH; Downard KM, 2010, 'Rapid Differentiation of Seasonal and Pandemic H1N1 Influenza through Proteotyping of Viral Neuraminidase with Mass Spectrometry', Analytical Chemistry, vol. 82, pp. 4584 - 4590, http://dx.doi.org/10.1021/ac100594j

Wong JWH; Schwahn AB; Downard KM, 2010, 'FluTyper - An Algorithm for Automated Typing and Subtyping of the Influenza Virus from High Resolution Mass Spectral Data.', BMC bioinformatics, vol. 11, pp. 2 - 13, http://dx.doi.org/10.1186/1471-2105-11-266

Schwahn AB; Wong JWH; Downard KM, 2010, 'Typing of human and animal strains of influenza virus with conserved signature peptides of matrix M1 protein by high resolution mass spectrometry', Journal of Virological Methods, vol. 165, pp. 178 - 185, http://dx.doi.org/10.1016/j.jviromet.2010.01.015

Wong JWH; Hogg PJ, 2010, 'Analysis of disulfide bonds in protein structures', Journal of Thrombosis and Haemostasis, vol. 8, pp. 2345 - 2345, http://dx.doi.org/10.1111/j.1538-7836.2010.03894.x

Schwahn AB; Wong JWH; Downard KM, 2009, 'Signature peptides of influenza nucleoprotein for the typing and subtyping of the virus by high resolution mass spectrometry', Analyst, vol. 134, pp. 2253 - 2261, http://dx.doi.org/10.1039/b912234f

Wong JWH; Schwahn AB; Downard KM, 2009, 'ETISEQ - An algorithm for automated elution time ion sequencing of concurrently fragmented peptides for mass spectrometry-based proteomics', BMC bioinformatics, vol. 10, pp. 244 - 244, http://dx.doi.org/10.1186/1471-2105-10-244

Schwahn AB; Wong JWH; Downard KM, 2009, 'Subtyping of the influenza virus by high resolution mass spectrometry', Analytical Chemistry, vol. 81, pp. 3500 - 3506, http://dx.doi.org/10.1021/ac900026f

Wong J; Cagney G; Mcredmond J, 2009, 'Activity profiling of platelets by chemical proteomics', Proteomics, vol. 9, pp. 40 - 50, http://dx.doi.org/10.1002/pmic.200800185

Wong J; Sullivan M; Cagney G, 2008, 'Computational methods for the comparative quantification of proteins in label-free LCn-MS experiments', Briefings in Bioinformatics, vol. 9, pp. 156 - 165, http://dx.doi.org/10.1093/bib/bbm046

Wong J; Sullivan M; Cartwright H; Cagney G, 2007, 'msmsEval: Tandem mass spectra quality assessment for high-throughput proteomics', BMC bioinformatics, vol. 8, pp. 1 - 11, http://dx.doi.org/10.1186/1471-2105-8-51

Wong J; Maleknia SD; Downard K, 2005, 'Hydroxyl Radical Probe of the Calmodulin-Melittin Complex Interface by Electrospray Ionization Mass Spectrometry', Journal of the American Society for Mass Spectrometry, vol. 16, pp. 225 - 233, http://dx.doi.org/10.1016/j.jasms.2004.11.009

Wong J; Durante C; Cartwright H, 2005, 'Application of Fast Fourier Transform Cross-Correlation for the Alignment of Large Chromatographic and Spectral Datasets', Analytical Chemistry, vol. 77, pp. 5655 - 5661, http://dx.doi.org/10.1021/ac050619p

Wong J; Downard K, 2005, 'Performance of the Computer Algorithm COMPLX for the Detection of Protein Complexes in the Mass Spectra of Simulated Biological Mixtures.', International Journal of Mass Spectrometry, vol. 40, pp. 1187 - 1196, http://dx.doi.org/10.1002/jms.894

Wong J; Cartwright H, 2005, 'Deterministic projection by Growing Cell Structure Networks for Visualization of High-dimensionality Datasets', Journal of Biomedical Informatics, vol. 38, pp. 322 - 330, http://dx.doi.org/10.1016/j.jbi.2005.02.002

Wong J; Cagney G; Cartwright H, 2005, 'SpecAlign - Processing and Alignment of Mass Spectra Datasets', Bioinformatics, vol. 21, pp. 2088 - 2090, http://dx.doi.org/10.1093/bioinformatics/bti300

Wong JWH; Maleknia SD; Downard KM, 2004, 'Photochemical and Electrophysical Production of Radicals on Millisecond Timescales to Probe the Structure, Dynamics and Interactions of Proteins', Photochemical and Photobiological Sciences, vol. 3, pp. 741 - 748, http://dx.doi.org/10.1039/b315904c

Zhang S; Srinivasan M; Zhu H; Wong J, 2004, 'Grouping of Visual Objects by Honeybees', The Journal of Experimental Biology, vol. 207, pp. 3289 - 3298, http://dx.doi.org/10.1242/jeb.01155

Wong J; Maleknia SD; Downard K, 2003, 'Study of the Ribonuclease S-Protein-Peptide Complex Using a Radical Probe and Electrospray Ionization Mass Spectrometry', Analytical Chemistry, vol. 75, pp. 1557 - 1563, http://dx.doi.org/10.1021/ac026400h

Wong J; Downard K, 2003, 'COMPLX: A Computer Algorithm for the Detection of Protein-Ligand and Other Macromolecular Complexes in Mass Spectra', International Journal of Mass Spectrometry, vol. 38, pp. 573 - 581, http://dx.doi.org/10.1002/jms.474

Thoms JAI; Knezevic K; Harvey G; Huang Y; Seneviratne JA; Carter DR; Subramanian S; Skhinas J; Chacon D; Shah A; de Jong I; Beck D; Göttgens B; Larsson J; Wong JWH; Zanini F; Pimanda JE, 'Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells', , http://dx.doi.org/10.1101/2020.10.26.353797

Barbour JA; Ou T; Fang H; Yue NC; Zhu X; Wong-Brown MW; Yang H; Wong YT; Bowden NA; Wu S; Wong JWH, XPD protects CTCF-Cohesin binding sites from somatic mutagenesis, http://dx.doi.org/10.1101/2022.01.21.477237