Book Chapters
Brayford S; Schevzov G; Vos J; Gunning P, 2015, 'The role of the actin cytoskeleton in cancer and its potential use as a therapeutic target', in The Cytoskeleton in Health and Disease, pp. 373 - 391 (link is external)
Bonello T; Coombes J; Schevzov G; Gunning P; Stehn J, 2012, 'Therapeutic targeting of the actin cytoskeleton in cancer', in Cytoskeleton and Human Disease, pp. 181 - 200 (link is external)
Curthoys NM; Gunning PW; Fath T, 2011, 'Tropomyosins in Neuronal Morphogenesis and Development', in Nixon RA; Yuan A (ed.), CYTOSKELETON OF THE NERVOUS SYSTEM, edn. Advances in Neurobiology, SPRINGER, pp. 411 - 445 (link is external)
Hill MA; Gunning P, 1995, 'The cell cytoskeleton's functional requirement for localized mRNA', in Localized RNAs, edn. Original, Springer Publishing Company, New York, pp. 197 - 213
Journal articles
Jeong S; Lim S; Schevzov G; Gunning PW; Helfman DM, 2017, 'Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling.', Oncotarget (link is external)
Desouza-Armstrong M; Gunning PW; Stehn JR, 2017, 'Tumor suppressor tropomyosin Tpm2.1 regulates sensitivity to apoptosis beyond anoikis characterized by changes in the levels of intrinsic apoptosis proteins.', Cytoskeleton (Hoboken) (link is external)
Pleines I; Woods J; Chappaz S; Kew V; Foad N; Ballester-Beltrán J; Aurbach K; Lincetto C; Lane RM; Schevzov G, 2017, 'Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia', Journal of Clinical Investigation, vol. 127, pp. 814 - 829 (link is external)
Gateva G; Kremneva E; Reindl T; Kotila T; Kogan K; Gressin L; Gunning PW; Manstein DJ; Michelot A; Lappalainen P, 2017, 'Tropomyosin Isoforms Specify Functionally Distinct Actin Filament Populations In Vitro', Current Biology, vol. 27, pp. 705 – 713 (link is external)
Gunning PW; Hardeman EC, 2017, 'Tropomyosins', Current Biology, vol. 27, pp. R8 - R13 (link is external)
Conference Papers
Chisholm OT; Parisio M; Heaton A; Brown D; Gunning P, 2015, 'Blended strategies for learning about medicines development', in Collins L; Nangle P; Landrigan B; O’Connell A; Teale A (eds.), UNSW Learning and Teaching Forum - Blended Learning: Past, Present and Future, UNSW, UNSW, pp. 74 - 75, presented at UNSW Learning and Teaching Forum - Blended Learning: Past, Present and Future, UNSW, 16 - 16 October 2015
Oldfield R; Jalilian I; Pereira A; Gunning P; Knothe Tate ML, 2015, 'Live Multiplexed Imaging and Modeling of Stem Cell Mechanomics', in Proceedings of the 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI 2015), Institute of Electrical and Electronics Engineers ( IEEE ), presented at IEEE International Symposium on Biomedical Imaging, 16 - 19 April 2015 (link is external)
Knothe Tate ML; Gunning P; Sansalone V, 2014, 'Mapping the Mechanome: Retrospective and Prospective Approaches', in Mapping the Mechanome: Retrospective and Prospective Approaches, 7th World Congress of Biomechanics, pp. 14-IS-5274-WCB, presented at 7th World Congress of Biomechanics, 06 - 11 July 2014 (link is external)
Kee AJ; Lucas CA; Yang L; Szokolai RC; Martel N; Leong GM; Muscat GE; Hughes W; Cooney G; James DE, 2012, 'The actin regulatory protein Tropomyosin 5NM1 regulates glucose uptake and GLUT4 trafficking in the mouse.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY (link is external)
Hardeman EC; Darhed HA; Lee ASJ; Chen G; Shah J; Joya JE; Gunning PW, 2012, 'BLOOD BORNE AGENTS RESCUE REGENERATION IMPAIRED MUSCLE', in WOUND REPAIR AND REGENERATION, WILEY-BLACKWELL, pp. A59 - A59 (link is external)
Conference Posters
Hardeman EC; Kee AJ; Lucas CA; Chagan J; Gunning PW, 2016, 'Metabolic impact of targeting the tropomyosin/actin cytoskeleton to treat cancer', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, San Francisco, CA, Vol. 27, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), San Francisco, CA, 03 - 07 December 2016 (link is external)
Stehn J; Mariana A; Failes T; Ashokakumar V; Eiffe E; Heaton A; Hook J; Sivanandhan D; Arndt G; Gunning P, 2016, 'Synergistic action of first-in-class anti-tropomyosin compound, ATM-3507 (Anisina) and microtubule targeting inhibitors in pre-clinical models of non-small cell lung cancer (NSCLC)', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, Munich, GERMANY, Vol. 69, pp. S116 - S116, presented at 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Munich, GERMANY, 29 November - 02 December 2016 (link is external)
Jalilian I; Oldfield R; Gunning PW; Tate MLK, 2015, 'Live multiplexed imaging of stem cell mechanotransduction and mechanoadaptation.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 26 (link is external)
Suchowerska A; Chen B; Mueller J; Ittner A; Hardeman E; Ittner L; Janitz M; Gunning P; Fath T, 2013, 'Increased levels of actin filaments containing the tropomyosin Tm5NM1 regulate excitotoxicity in the mouse', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 24 (link is external)
Patents
Gunning P; Stehn J; McCluskey A; Butler T; Dixon I, 2007, Compounds for treating Cancer, Australia, Patent No. Australian Provisional Patent Application No 2007906570, Patent Agent:
Gunning P; Stehn J; Schevzov G, 2005, Identification of compounds for the treatment of proliferative disorders, Australia, Patent No. Australian Provisional Patent Application No 2004906888, Patent Agent:
Conference Presentations
Jalilian I; Oldfield R; Gunning PW; Tate MLK, 2015, 'Live multiplexed imaging of stem cell mechanotransduction and mechanoadaptation', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 26 (link is external)
Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 - 10 December 2014 (link is external)
Hardeman EC; Yang L; Kee AJ; Polishchuk E; Polishchuk R; Pleines I; Kile B; Weigert R; Gunning PW, 2014, 'A novel actin filament population defined by the tropomyosin Tm4 regulates ER-to-Golgi trafficking.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 - 10 December 2014 (link is external)
Brayford S; Schevzov G; Hardeman EC; Bear JE; Gunning PW, 2014, 'Tropomyosin 5a/b actin filaments collaborate with arp2/3 actin filaments to regulate cell motility.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 - 10 December 2014 (link is external)
Schevzov G; Wang B; Hook JW; Tonthat C; Pleines I; Kile B; Hardeman EC; Gunning PW, 2014, 'Distinct Actin Filament Networks Modulate Different Cell Signalling Pathways Involved in Cell Proliferation and Senescence.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 - 10 December 2014 (link is external)
Conference Abstracts
Stehn JR; Stevenson A; Spoerri L; Daignault SM; Gabrielli B; Eiffe E; Gunning PW; Haass N, 2016, 'Developing a new melanoma drug', in AUSTRALASIAN JOURNAL OF DERMATOLOGY, WILEY-BLACKWELL, Vol. 57, pp. 11 - 12 (link is external)
Stehn J; Currier M; Chen D; Eiffe E; Heaton A; Hook J; Gunning P; Cripe T, 2016, 'First-in-class cytoskeletal targeting drug, Anisina, enhances effectiveness of microtubule inhibitors in a preclinical model of neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Fort Lauderdale, FL, Vol. 76, presented at AACR Special Conference on Advances in Pediatric Cancer Research - From Mechanisms and Models to Treatment and Survivorship, Fort Lauderdale, FL, 09 - 12 November 2015 (link is external)
Obeidy P; Sobey TL; Pandzic E; Nicovich PR; Coster A; Gunning P; Boecking T, 2015, 'Actin Tropomyosin Assembly Intermediates', in BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 108, pp. 298A - 298A (link is external)
Fath T; Brettle M; Janitz M; Gunning P, 2015, 'Manipulation of the actin cytoskeleton promotes neurite outgrowth on inhibitory substrates', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 311 - 311, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australa, Cairns, AUSTRALIA, 23 - 27 August 2015 (link is external)
Segueira VB; Stehn JR; Haass N; Bonello T; Guven K; Desouza M; Schevzov G; Kottyan G; McCluskey A; Bischof L, 2012, 'Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72 (link is external)